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Current year restructuring costs Restructuring Reserve, Accrual Adjustment Lessee, Operating Lease, Liability, to be Paid, Year Two 2026 Indefinite-Lived Intangible Assets, Major Class Name [Domain] Prepaid Expense and Other Assets, Current [Abstract] Weighted Average Number of Shares Outstanding, Diluted Weighted-average shares of common stock outstanding, diluted Weighted Average Number of Shares Outstanding, Diluted, Total Entity File Number Securities Act File Number OCI, Debt Securities, Available-for-Sale, Unrealized Holding Gain (Loss), before Adjustment, after Tax Unrealized gain on short-term investments Unrealized gain (loss) on short-term investments Cover [Abstract] Other Expenses Other unallocated expenses Prepaid expenses and other current assets Prepaid Expense and Other Assets, Current Total Percentage of shares of common stock outstanding Share-Based Compensation Arrangement by Share-Based Payment Award, Percentage of Outstanding Stock Maximum Investments Investments [Domain] US Treasury Securities [Member] U.S. Treasury obligations Sale of Stock Sale of Stock [Domain] General and Administrative Expense, Total General and administrative General and Administrative Expense General and administrative Series B Preferred Stock [Member] Series B Preferred Stock [Member] Business Combination, Asset Acquisition, Transaction between Entities under Common Control, and Joint Venture Formation [Abstract] Stock Issued During Period, Shares, Acquisitions Stock Issued During Period, Shares, Acquisitions Subsequent Event [Table] Number of shares issued under the plan Share-Based Compensation Arrangement by Share-Based Payment Award, Shares Issued in Period Reclassification of warrant liability to additional paid-in capital Adjustments to Additional Paid in Capital, Warrant Issued Reclassification of pre-funded stock warrants Goodwill [Member] Operating Lease, Expense Operating lease rental expense Gain (Loss) on Extinguishment of Debt Gain (Loss) on Extinguishment of Debt Weighted average exercise price per share, Vested and expected to vest Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Outstanding, Weighted Average Exercise Price Incured Restructuring Charges Restructuring-Related Charge Restructuring Charges New Accounting Pronouncements, Policy [Policy Text Block] Recent Accounting Pronouncements Lessee, Operating Lease, Liability, to be Paid, Maturity [Table Text Block] Summary of Future Minimum Rental Payments Under Non Cancelable Operating Leases Antidilutive Securities Excluded From Computation Of Earnings Per Share [Line Items] Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items] Gain (Loss) on Disposition of Assets Gain (Loss) on Disposition of Assets, Total Gain on sale of assets Vesting period Share-Based Compensation Arrangement by Share-Based Payment Award, Award Vesting Period Reclassification to equity Equity, Fair Value Adjustment Royalty Purchase Liability [Table] Royalty Purchase Liability [Table] Royalty purchase liability. 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Initial Public Offering And Concurrent Private Placements [Member] Initial Public Offering and Concurrent Private Placements [Member] Research and Development Expense, Total Research and development Research and Development Expense Research and development Restructuring Charges [Abstract] Leases Lessee, Operating Leases [Text Block] Statement of Cash Flows [Abstract] Summary of Activity Related to Stock Option Grants Share-Based Payment Arrangement, Option, Activity [Table Text Block] Equity Equity [Text Block] Computer Hardware and Software Computer Equipment [Member] Net loss Net loss Net loss Aggregate intrinsic value of options outstanding Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Intrinsic Value Total operating lease expense Operating Lease, Cost Workforce Reduction Rate Workforce Reduction Rate Workforce Reduction Rate Workforce Reduction Rate Warrant expiration term Warrants and Rights Outstanding, Term Preferred Stock, Convertible, Shares Issuable Series B non-voting convertible preferred stock | shares Expected dividend yield Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Dividend Rate Obsidian [Member] Obsidian [Member] Operating cash flows for operating leases Operating Lease, Payments Assets Assets [Abstract] Equity Holders Valuation Amount Equity Holders Valuation Amount Equity holders valuation amount Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Risk Free Interest Rate Risk-free interest rate Increase (Decrease) in Prepaid Expense and Other Assets, Total Prepaid expenses and other current assets Increase (Decrease) in Prepaid Expense and Other Assets Restructuring and Related Activities [Abstract] Document Fiscal Year Focus Document Fiscal Year Focus Investing activities: Cash Provided by (Used in) Investing Activity, Including Discontinued Operation [Abstract] Accounts Payable, Current, Total Accounts payable Accounts Payable, Current Research and Development Research and Development Expense [Member] Other assets Increase (Decrease) in Other Noncurrent Assets Other assets 2012 Equity Incentive Plan Equity Incentive Plan [Member] Equity Incentive Plan. Restructuring Cost and Reserve [Line Items] Fair Value Disclosures [Abstract] Commitments and Contingencies Disclosure [Abstract] Lessee, Operating Lease, Liability, to be Paid, Year One 2025 Intangible Asset, Indefinite-Lived [Table] Net Income (Loss) Available to Common Stockholders, Basic Net Income (Loss) Available to Common Stockholders, Basic, Total Net loss attributable to common stockholders, basic Debt Instrument Debt Instrument [Axis] Share-Based Payment Arrangement [Abstract] April Twenty Eight, Two Thousand Twenty Three [Member] April 28, 2023 [Member] April Twenty Eight, Two Thousand Twenty Three [Member] Sale of Stock Sale of Stock [Axis] Long-term Debt and Lease Obligation, Current, Total Lease liabilities Long-Term Debt and Lease Obligation, Current Lease liabilities, current Cash Provided by (Used in) Investing Activity, Including Discontinued Operation Cash provided by investing activities Program Expenses Program Expenses Program expenses Title of 12(b) Security Title of 12(b) Security Schedule of Segment Reporting Information, by Segment [Table] Contingent value rights Contingent Value Rights Contingent Value Rights Weighted average exercise price per share, Forfeited/Expired Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Forfeitures in Period, Weighted Average Exercise Price Money Market Funds [Member] Money Market Funds Related Party Related and Nonrelated Parties [Domain] Class of Warrant or Right [Line Items] Office Office [Member] Office. Lessee, Operating Lease, Liability, to be Paid, Remainder of Fiscal Year Remainder of 2024 Legal Entity [Axis] Changes in operating assets and liabilities: Adjustment to Reconcile Net Income to Cash Provided by (Used in) Operating Activity, Increase (Decrease) in Operating Capital [Abstract] Schedule of Property Plant and Equipment Property, Plant and Equipment [Table Text Block] Accretion of Redeemable Convertible Preferred Stocks to Redemption Value Accretion of Redeemable Convertible Preferred Stocks to Redemption Value Accretion of redeemable convertible preferred stock to redemption value Accretion (amortization) of redeemable convertible preferred stock to redemption value Weighted average exercise price per share, Outstanding beginning balance Weighted average exercise price per share, Outstanding ending balance Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Exercise Price Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Table] Fair Value, Recurring and Nonrecurring [Table] Additional Paid-in Capital Additional Paid-in Capital [Member] Pre funded Warrants [Member] Pre funded Warrants [Member] Pre funded Warrants [Member] Goodwill and acquired intangible asset Goodwill and Intangible Assets, Intangible Assets, Indefinite-Lived, Policy [Policy Text Block] Two Thousand Nineteen Employee Stock Purchase Plan [Member] Two Thousand Nineteen Employee Stock Purchase Plan [Member] Nonmonetary Transaction Type [Domain] Income Statement Location Statement of Income Location, Balance [Axis] Shareholder Rights Agreement Shareholder Rights Agreement [Member] Shareholder Rights Agreement [Member] Trading Symbol Trading Symbol Property, Plant and Equipment Disclosure [Text Block] Property and equipment Liabilities, Fair Value Adjustment Additions Related Party Transaction [Table] Schedule Of Related Party Transactions By Related Party [Table] Subsequent Event Type Subsequent Event Type [Axis] Financing activities: Cash Provided by (Used in) Financing Activity, Including Discontinued Operation [Abstract] Expected term (in years) Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Term Accrued Expenses Accounts Payable and Accrued Liabilities Disclosure [Text Block] Entity Ex Transition Period Entity Ex Transition Period Total Lessee, Operating Lease, Liability, to be Paid Lease Rental payments 2023 Employment Inducement Award Plan [Member] Employment Inducement Award Plan [Member] Less: imputed interest Lessee, Operating Lease, Liability, Undiscounted Excess Amount Maximum Aggregate Offering Price Registration Payment Arrangement, Maximum Potential Consideration Fourth Tranche. Fourth Tranche Fourth Tranche [Member] Goodwill and Intangible Asset Impairment, Total Goodwill and Intangible Asset Impairment Goodwill And Intangible Asset Impairment Accumulated Other Comprehensive (Loss) Income Equity Components [Axis] Equity Component Equity Component [Domain] Business Combination [Axis] 2019 Incentive Award Plan Two Thousand Nineteen Incentive Award Plan [Member] 2019 Incentive Award Plan. Prepaid Insurance Prepaid insurance Late filing penalty Late filing penalty Late filing penalty Stock options granted purchase shares Stock Issued During Period, Shares, Employee Stock Purchase Plans Maximum Offering Issuance And Sale Expense Covered In Company Securities Maximum Offering Issuance And Sale Expense Covered In Company Securities Maximum offering issuance and sale expense covered in company securities. Statement of Comprehensive Income [Abstract] Maximum [Member] Maximum Member Beginning Balance Liabilities, Fair Value Disclosure Liabilities, Fair Value Disclosure, Total Ending Blalnce Statistical Measurement Statistical Measurement [Axis] Weighted average exercise price per share, Exercised Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Exercises in Period, Weighted Average Exercise Price Royalty agreement receivable Royalty Agreement Receivable Royalty agreement receivable. Prepaid clinical expenses Prepaid Expense, Current, Total Prepaid Expense, Current Common Stock, Value, Issued Common Stock, Value, Issued, Ending Balance Common Stock, Value, Issued, Beginning Balance Common Stock, Value, Issued, Total Common stock, $0.001 par value: 200,000,000 shares authorized; 75,462,390 shares issued and outstanding at March 31, 2026 and December 31, 2025 Net Income (Loss) Available to Common Stockholders, Diluted Net Income (Loss) Available to Common Stockholders, Diluted, Total Net loss attributable to common stockholders, diluted Organization And Description Of Business [Table] Organization And Description Of Business [Table] Organization and description of business. Stock Options Stock Options [Member] Stock options. Liabilities subject to compromise early contract termination fees Liabilities Subject to Compromise, Early Contract Termination Fees Warrants and Rights Outstanding Warrant liability Laboratory Equipment Equipment [Member] Related Party Transaction, Amounts of Transaction Related Party Transaction Amounts At-the-market Offering [Member] A T M Offering [Member] At the market offering Share-Based Compensation Arrangement by Share-Based Payment Award, Discount from Market Price, Offering Date ShareBasedCompensationArrangementByShareBasedPaymentAwardDiscountFromMarketPriceOfferingDate Expected stock price volatility Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Volatility Rate Preferred stock, shares authorized (shares) Preferred Stock, Shares Authorized Finite-Lived Intangible Assets by Major Class Finite-Lived Intangible Assets by Major Class [Axis] Related Party Transaction, Description of Transaction Description of transaction Related Party Transaction [Line Items] Related Party Transaction [Line Items] Business Combination [Table] Entity Registrant Name Entity Registrant Name Exercise price Share-Based Payment Arrangement, Option, Exercise Price Range, Exercisable, Weighted Average Exercise Price Conversion of Stock, Shares Issued Number of conversion shares issued Subsequent Events [Abstract] Income Tax Expense (Benefit) Income Tax Expense (Benefit), Total Income tax benefit Income tax benefit Amended Royalty Agreements Amended Royalty Agreements [Member] Amended royalty agreements. Share Based Compensation Arrangement By Share Based Payment Award [Line Items] Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items] Current year restructuring costs Current year restructuring costs Current year restructuring costs Entity Common Stock, Shares Outstanding Entity Common Stock, Shares Outstanding Lessee, Operating Lease, Remaining Lease Term Lessee, operating lease, remaining lease term Organization And Description Of Business [Line Items] Organization And Description Of Business [Line Items] Organization and description of business. Payment of employee severance and related costs Payments for Restructuring Total assets Assets Schedule Of Property Plant And Equipment [Table] Property, Plant and Equipment [Table] Weighted average remaining contractual life, Vested and exercisable Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Weighted Average Remaining Contractual Term Income Statement [Abstract] Restructuring Cost [Table] Dr. Chang [Member] Dr. Chang [Member] Summary of Supplemental Cash Flow Information Related to Leases Schedule Of Supplemental Cash Flow Information Related To Leases Table [Text Block] Schedule of supplemental cash flow information related to leases. Deferred tax benefit Deferred Income Tax Expense (Benefit) Deferred Income Tax Expense (Benefit), Total Stock Issued During Period, Shares, New Issues Sale of common stock warrants, net of issuance costs, shares | shares Net loss per share of common stock, diluted Earnings Per Share, Diluted Earnings Per Share, Diluted, Total Schedule of Segment Reporting Information, by Segment [Table Text Block] Summarizes the significant expense categories reviewed Title and Position [Domain] Asset Acquisition [Axis] City Area Code City Area Code Common Stock Warrants Common Stock Warrants [Member] Common stock warrants. Potential Future Net Potential Future Net Sale of common stock in registered direct offering, issuance costs Common Stock Issuance Costs Common stock issuance costs. Business Combination [Line Items] Counterparty Name Counterparty Name [Domain] Litigation Settlement, Gain Gain on litigation settlement Segment Reporting Information [Line Items] Lease Expiration Date Award Date [Axis] Cash and cash equivalents Cash and Cash Equivalents, Policy [Policy Text Block] Property, Plant and Equipment, Net, Ending Balance Property, Plant and Equipment, Net, Beginning Balance Property and equipment, net Property and equipment, net Property, Plant and Equipment, Net Operating Income (Loss) Loss from operations Award Date [Domain] Derecognition Of Lease Liability And Right-Of-Use Asset Due To Lease Termination Derecognition Of Lease Liability And Right-Of-Use Asset Due To Lease Termination Derecognition of lease liability and right-of-use asset due to lease termination Accumulated Deficit Retained Earnings [Member] Cash and Cash Equivalents [Axis] Share-based compensation expense Share-Based Payment Arrangement, Noncash Expense Share-based Payment Arrangement, Noncash Expense, Total Asset Acquisition, Consideration Transferred Asset Acquisition, Consideration Transferred, Total Contingent value Lease liabilities, net of current portion Operating Lease, Liability, Noncurrent Level 1 Fair Value, Inputs, Level 1 [Member] Cash provided by financing activities Cash Provided by (Used in) Financing Activity, Including Discontinued Operation Summary of Components of Lease Expense Lease, Cost [Table Text Block] Schedule Of Prepaid Expenses And Other Current Assets Schedule of Other Current Assets [Table Text Block] Schedule of Stockholders' Equity Note, Warrants or Rights [Table Text Block] Schedule of Common Stock Warrants Nonoperating Income (Expense) [Abstract] Other income : Accrued research and development Accrued Research And Development Expenses Current Accrued research and development expenses current. Research and development expenses 2019 Employee Stock Purchase Plan Thousand And Nineteen Employee Stock Purchase Plan [Member] 2019 Employee stock purchase plan. US Government Corporations and Agencies Securities [Member] U.S. government agency securities Dilutive Securities Excluded from Computation of Diluted Weighted Average Shares of Common Stock Outstanding Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table Text Block] Income Tax Jurisdiction [Domain] Entity Interactive Data Current Entity Interactive Data Current Income Statement Location Statement of Income Location, Balance [Domain] Operating activities: Cash Provided by (Used in) Operating Activity, Including Discontinued Operation [Abstract] Furniture and Fixtures Furniture and Fixtures [Member] Convertible Preferred Stock, Shares Issued upon Conversion Convertible Preferred Stock, Shares Issued upon Conversion Noncash interest expense Paid-in-Kind Interest Conversion of Stock, Shares Outstanding Conversion of Stock, Shares Outstanding Number of conversion shares outstanding Research and Development Arrangement with Federal Government, Costs Incurred, Net Federal research and development tax credits Stock Issued During Period Shares Common Stock Warrants Exercised 1 Stock Issued During Period Shares Common Stock Warrants Exercised 1 Exercise of common stock warrants (Shares) Entity Tax Identification Number Entity Tax Identification Number Series B Redeemable Convertible Preferred Stockholders [Member] Series B Redeemable Convertible Preferred Stockholders [Member] Organization, Consolidation and Presentation of Financial Statements Disclosure [Text Block] Organization and description of business Local Phone Number Local Phone Number Recent Accounting Pronouncements – Issued but not yet adopted New Accounting Pronouncements Issued But Not Yet Adopted Policy Policy [Text Block] New accounting pronouncements issued but not yet adopted policy. Recent Accounting Pronouncements Not Yet Adopted Reclassification Of Warrant Liability To Additional Paid In Capital Reclassification Of Warrant Liability To Additional Paid In Capital Reclassification of warrant liability to additional paid-in capital Accounting Policies [Abstract] Cash Investments and Cash Investments and Cash, Total Royalty Purchase Liability [Abstract] Royalty purchase liability. Lessee, Operating Lease, Liability, to be Paid, Year Four 2028 And After Class of Stock [Domain] Number of shares available for issuance Share-Based Compensation Arrangement by Share-Based Payment Award, Number of Shares Available for Grant Estimated recognition weighted-average amortization period Share-Based Payment Arrangement, Nonvested Award, Cost Not yet Recognized, Period for Recognition Entity Emerging Growth Company Entity Emerging Growth Company Weighted average remaining contractual life, Vested and expected to vest Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Outstanding, Weighted Average Remaining Contractual Term Indefinite-Lived Intangible Assets [Axis]